COMPARATIVE SAFETY AND EFFECTIVENESS OF PERINATAL ANTIRETROVIRAL THERAPIES FOR HIV-INFECTED WOMEN AND THEIR CHILDREN: SYSTEMATIC REVIEW AND NETWORK META-ANALYSIS INCLUDING DIFFERENT STUDY DESIGNS.

BACKGROUND:Nearly all newly infected children acquire Human Immunodeficiency virus (HIV) via mother-to-child transmission (MTCT) during pregnancy, labour or breastfeeding from untreated HIV-positive mothers.Antiretroviral therapy (ART) is the standard care for pregnant women with HIV.However, evidence of ART effectiveness and harms in infants and c

Steve Titmarsh,1 Michele Poliziani,2 Richard E Russell3 1M&F Health, London EC1N 8TE, UK; 2Opinion Health, London W1F 8QA, UK; 3Nuffield Department of Medicine, University of Oxford, Oxford OX3 7FZ, UKCorrespondence: Steve TitmarshM&F Health, 35–37 Kirby Street, London EC1N 8TE, UKTel +44 207 492 1793Email [email protected]

Abstract Background Prader-Willi syndrome (PWS) is a rare neurodevelopmental disorder resulting from abnormalities on chromosome 15q11.2-q13.These genetic anomalies pose significant challenges in anesthetic management when PWS patients undergo bariatric surgery.Methods We present five instances of anesthetic management in three PWS patients who und

Over the past 20 years, rolled compacted concrete (RCC) dams have continued to be built in many countries because of their technical and economic advantages over conventional dams of vibrating concrete and embankment dams.The aim of this study is the development of new structural and technological solutions in RCC dams in order to reduce the consum